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Alzheimer's Disease Is A Brain Disorder That Results In Progressive Memory Deterioration. Considered The Primary Reason Why A Person Experiences Dementia, Alzheimer's Affects Family Members In A Profound Way. Welcome To AlzheimersDementiaInfo.com. We Are Here To Provide A Free Educational Resource About Alzheimer's Disease And Dementia. As
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Alzheimer's Toxin May Be Key To Slowing Disease
Author: Baron Grove
Australian scientists say they have identified a toxin which
plays a key role in the onset of Alzheimer's, raising hope that
a drug targeting the toxin could be developed to slow the
degenerative brain disease.
The toxin, called quinolinic acid, kills nerve cells in the
brain, leading to dysfunction and death, the scientists said.
"Quinolinic acid may not be the cause of Alzheimer's disease,
but it plays a key role in its progression," Alzheimer's
researcher Dr Karen Cullen from the University of Sydney said in
a statement. "It's the smoking gun, if you like."
"While we won't be able to prevent people from getting
Alzheimer's disease, we may eventually, with the use of drugs,
be able to slow down the progression."
Alzheimer's is a brain-destroying disease that affects millions
of people around the world. As the population gets steadily
older, experts estimate numbers will balloon to as many as 16
million in the United States alone by 2015.
More than 200,000 people have Alzheimer's disease in Australia
and the number is expected to rise to 730,000 by 2050.
Outward symptoms start with memory loss, which progresses to
complete helplessness as brain cells are destroyed. In the
brain, neurons die as messy plaques and tangles of protein form.
The Alzheimer's research team from Sydney's St Vincent's
Hospital, the University of Sydney and Japan's Hokkaido
University found quinolinic acid neurotoxicity in the brains of
dementia patients.
Quinolinic acid is part of a biochemical pathway called the
kynurenine pathway which is also found in other brain disorders,
including Huntington's disease and schizophrenia.
The scientists said there were several drugs in an advanced
stage of development for other conditions which targeted this
pathway and that these drugs, which still need to be tested,
could be used to complement other treatments for Alzheimer's.
About the author:
Baron Grove http://www.refridgerator.net
Article Keywords:
Alzheimer's |
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A Quick Note
From The Publisher...
If you like the article above, you may be
interested in the following article which is also related to Alzheimer's...
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Memory Loss in Alzheimer's Disease |
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Do you know your date of birth? The name of the President or
Prime Minister? These are questions that are regularly used to
test for memory loss - the first symptom of Alzheimer's disease.
Although memory loss occurs in all cases of Alzheimer's disease,
it can be difficult to detect in the early stages as many
patients manage to cover it up well during tests as a matter of
pride.
It's the recent things we've done such as in the last hours,
days or even weeks that are the first memories to be lost in
Alzheimer's patients.
However, while those things that are placed in our short term
memory are the first to go it's only much later as the
Alzheimer's condition has become much more severe does the past
or longer term memory become affected.
This makes the degree or memory loss a very useful tool in
assessing the presence and scope of the disease as if the
patient is co-operative and asked in a pleasant way the results
can be very revealing.
The... |
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Alzheimer's, Alzheimer's Prevention News |
Free seminar on Alzheimer's planned in Shelburne (The Burlington Free Press) SHELBURNE -- The public is invited to "Current Minded: How People with Alzheimer's Disease are Remembering Who We Are," at 6:30 p.m., Jan. 21 at The Arbors at Shelburne senior living community. Michael Verde, founder of Memory Bridge, will present a seminar on how people with Alzheimer's disease and dementia are as present in the world as those without memory impairments. Verde will also address ... Bill introduced to study those affected by Alzheimer’s disease (North Little Rock Times) Former University of Arkansas Athletic Director Frank Broyles and representatives from the state House and Senate gathered Dec. 8 to introduce a bill that will create a government mandated task force, to study the needs of those affected by Alzheimer’s disease and related dementias. Intellect Neurosciences, Inc. Grants to Top Tier Global Pharmaceutical Company License to Certain Alzheimer's Patents ... (PR Newswire via Yahoo! Finance) Intellect Neurosciences, Inc. , a biopharmaceutical company focused on development of disease-modifying therapeutic agents for the treatment and prevention of Alzheimer's disease , announced today that it has granted a non-exclusive License to a top-tier global pharmaceutical company regarding certain of Intellect's patents and patent applications related to antibodies and methods of treatment ... The 'not so old' suffer from Alzheimer's too: study (AFP via Yahoo! News) Alzheimer's disease affects not only the elderly, said a study Monday that found 14 percent of the estimated 500,000 Canadians suffering from dementia are under the age of 65. |
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